Sparing carbapenem usage

Carbapenem-resistant Enterobacteriaceae and the correlation between carbapenem and fluoroquinolone usage and resistance in the US military health system.

Whether carbapenem or fluoroquinolone usage is correlated with carbapenem-resistant Enterobacteriaceae (CRE) has not been investigated at the level of an entire US nationwide managed health care system. We analyzed 75 million person-years of surveillance and 1,969,315 cultures from all 266 hospitals in the geographically dispersed US military health system. Incidences of CRE remained under 1 ca...

Association of ertapenem and antipseudomonal carbapenem usage and carbapenem resistance in Pseudomonas aeruginosa among 12 hospitals in Queensland, Australia.

OBJECTIVES The objective of this study was to determine the association between ertapenem and antipseudomonal carbapenem use and carbapenem resistance in Pseudomonas aeruginosa in 12 hospitals in Queensland, Australia. METHODS Data on usage of ertapenem and other antipseudomonal carbapenems, measured in defined daily doses per 1000 occupied bed-days, were collated using statewide pharmacy dis...

Laparoscopic Fertility Sparing Management of Cervical Cancer

Increase of Carbapenem-Resistant Acinetobacter baumannii Infection in Acute Care Hospitals in Taiwan: Association with Hospital Antimicrobial Usage

OBJECTIVE Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as an important pathogen causing healthcare-associated infections (HAIs) in Taiwan. The present study is aimed to investigate the epidemiology of HAIs caused by CRAB and the association of CRAB infection and hospital usage of different antimicrobials. METHODS Two nationwide databases in the period 2003 to 2008, the Taiw...

Carbapenem-resistant Acinetobacter baumannii

To the editor: We read with interest the paper of Hrabák et al. [1] on the isolation of a blaNDM-1-carrying Acinetobacter baumannii strain. However, although the authors believed to be the first in the Czech Republic to report on a New Delhi metallo-beta-lactamase-1 (NDM-1)-producing bacterium, there have been other reports on the same A. baumannii strain in the country [2,3]. Here, we would li...